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Yale Team Develops Clip-on Monitor to Detect Coronavirus Exposure

1/23/2022

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Engineers from Yale University have developed a wearable device that can help individuals assess whether they have been exposed to SARS-CoV-2, the coronavirus that causes COVID-19. The cheap device can clip onto a person’s clothes and capture aerosolized viral particles in the surrounding environment.

From rapid tests to vaccines, many extraordinary innovations have helped us navigate this global pandemic. While we have several ways to determine whether a person has been infected with SARS-CoV-2, we still can only guess when and how someone has been exposed to the virus.

This innovation from a team of Yale University researchers is hoping to fill that surveillance gap. Called the Fresh Air Clip, the device is cheap, designed to attach to a person’s collar and capture aerosolized viral particles around a person’s mouth and nose.

The clip captures viral particles on a polydimethylsiloxane (PDMS) surface. At the end of a day, or several days, a wearer removes the clip and sends it to a lab, which uses polymerase chain reaction (PCR) analysis to determine the presence of SARS-CoV-2.

A new study is reporting on several tests of the Fresh Air Clip establishing it can effectively capture airborne viral particles. One experiment involved supplying the clips to several volunteers who wore the monitors for up to five days. Of the 62 monitors deployed, five returned positive results, showing exposure to SARS-CoV-2.

“Of the positive Fresh Air Clips, four were worn by restaurant servers and one was worn by a homeless shelter staff person,” the study shows. “Notably, two positive samples collected in restaurants with indoor dining were found to have high viral load when compared to the other samples (>100 copies per clip), suggestive of close contact with one or more infected individuals.”

As well as establishing the wearable monitor as being able to capture detectable levels of viral particles, the researchers note the device is sensitive enough to catch exposure events at sub infectious doses. This suggests the volume of viral particles picked up by the monitor allows for the quantification of environmental exposure to the virus. This is important, as it means the device does not simply offer an indication of viral exposure but a measure of the level of exposure.

Krystal Pollitt, a researcher working on the device, says one interesting potential use for the device could be to test the effectiveness of ventilation settings in COVID positive patient hospital rooms. Speaking to Yale News recently, Pollitt said her team found airborne traces of SARS-CoV-2 in hospital rooms that were thought to be well ventilated.

“We found this to be really interesting because we know that one of the infection control measures that is being highly recommended is enhanced ventilation,” said Pollitt. “Within the hospital network we had very high air change rates. Despite having those high air change rates, we could still detect airborne levels across the room.”

In its current form, the Fresh Air Clip can screen indoor environments and establish whether they are high-risk areas for exposure. Pollitt also said the wearable can also be used to identify indoor exposure events days before positive cases appear.

“The Fresh Air Clip can be useful for early identification of exposure events and allow for rapid action to be taken,” Pollitt said. “Exposed individuals can get tested or quarantine to prevent potential community transmission.”

The next big step for the device will be to develop ways for the monitor to offer real-time notification of viral exposure, in much the same way a radiation strip can immediately notify a wearer they are exposed to gamma or x-rays. Pollitt says she is interested in further developing the device with real-time exposure notifications.
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“It’s key to report back results quick,” Pollitt says. “We are keen to incorporate techniques for real-time SARS-CoV-2 detection.”
The new study was published in the journal Environmental Science & Technology Letters.

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Ford Could Use Social-Distance Buzzing Wristbands To Reopen Plants

4/26/2020

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A dozen Ford Motor Co. workers are experimenting with wearable social-distancing devices that could be deployed more widely once the carmaker reopens idled manufacturing plants.

The small group of volunteers at a Ford factory in Plymouth, Michigan, are trying out watch-like wearables that vibrate when employees come within six feet of each other, said Kelli Felker, a company spokeswoman. The aim is to keep workers from breaching the distance that health experts recommend to avoid spreading the coronavirus.

The social-distancing device could be part of a broader array of new safety protocols Ford deploys as it resumes production as early as next month after at least a roughly six-week shutdown. The automaker is also expected to subject all workers entering a facility to a thermal-imaging scan to detect a fever. And it will provide staff with masks and, in some cases, plastic face shields, Felker said. The company is devising the measures along with the United Auto Workers union.

“Ford and the UAW are working closely to identify different ways to keep our people safe while they are at work,” Felker said.

The Samsung Electronics Co. smartwatches Ford is piloting use software from closely held technology firm Radiant RFID, according to a spokesman for the Austin, Texas-based company. The devices utilize Bluetooth short-wave and low-power technology to detect proximity and clustering of workers.

In near real-time, workers receive a vibration and a color-coded warning on the watch to let them know when they are closer than six feet to another person. Supervisors also receive alerts and reports that can be used to monitor social distancing and clustering in the workplace, according to Radiant.

Ford has been piloting the new safety procedures at factories where it’s now producing ventilators and respirators to supply hospitals fighting the COVID-19 pandemic. Those practices – which include requiring workers to complete a daily online survey on their health and those they’re in contact with – are expected to be rolled out to the company’s traditional auto factories as they reopen.
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The automaker hasn’t set a date for when it plans to resume production.
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Apple Creates Coronavirus Screening App and Website

3/29/2020

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Apple on Friday released a COVID-19 website and app with a screening tool and other information about the coronavirus outbreak. Apple said the app and site are meant to "make it easy for people across the country to get trusted information and guidance at a time when the US is feeling the heavy burden of COVID-19." 

They were developed in partnership with the Centers for Disease Control and Prevention, the White House coronavirus task force, and the Federal Emergency Management Agency. 

The COVID-19 app and website include a screening tool that asks users to answer a series of questions around risk factors, recent exposure, and symptoms, Apple said in a release. Based on their responses, users will receive CDC recommendations on the next steps, including "guidance on social distancing and self-isolating, how to closely monitor symptoms, whether or not a test is recommended at this time, and when to contact a medical provider." 

Apple said the screening tool doesn't replace instructions from doctors and health care providers or guidance from state and local health authorities. 

"To help you stay informed, understand symptoms, and take proper steps to protect your health, Apple has created a COVID-19 website and a US app in partnership with the CDC," said Apple CEO Tim Cook in a tweet Friday. "As always, the data is yours, and your privacy is protected. Stay safe and healthy."

In addition to the screening tool, Apple said the app and website would offer answers to frequently asked questions about the coronavirus as well as up-to-date information from the CDC, including best practices for washing hands and how to monitor symptoms.
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Earlier this week, Apple updated its digital assistant Siri to help guide those worried about coronavirus symptoms. Summoned by asking Siri, "do I have coronavirus," the assistant will respond with the survey that uses yes and no answers to try to guide people on potential next steps.
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Can Smart Thermometers Track the Spread of the Coronavirus?

3/22/2020

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A company that makes internet-connected thermometers has followed the flu more closely than the C.D.C. can. Now the devices may be turning up cases of COVID-19.

A company that uses internet-connected thermometers to predict the spread of the flu says it is tracking the coronavirus in real-time – something that had been impossible, given the lack of testing for the disease.

Kinsa Healthhas sold or given away more than a million smart thermometers to households in which two million people reside, and thus can record fevers almost as soon as consumers experience them.

For the last few years, Kinsa’s interactive maps have accurately predicted the spread of flu around the United States about two weeks before the Centers for Disease Control and Prevention’s surveillance tool, the weekly FluView tracker.

The thermometer data “acts as an early warning system for illness spreading,” said Inder Singh, the company’s founder. The C.D.C.’s system lags because it relies on weekly reports from hundreds of doctors’ offices and hospital emergency rooms about what symptoms they are seeing in patients.

Company scientists are uniquely positioned to identify unusual clusters of fever because they have years of data for expected flu cases in each ZIP code. A sudden spike that far exceeds estimates for flu for a given date may well indicate the coronavirus has arrived.

Medical experts were enthusiastic about the possibility that smart thermometers could be used to track the virus in the United States. Having millions of data points allows Kinsa to produce daily maps showing which counties are seeing spiking fevers.

The most common symptoms of infection with the coronavirus is a fever – about 90% of patients suffer from it, according to the World Health Organization.

“This is very, very exciting,” said Dr. William Schaffner, a professor of preventive medicine at Vanderbilt University. “This is 21st-century disease surveillance, and we’ve been rooted in the mid-20th century with something very labor-intensive.”

Dr. Peter J. Hotez, dean of the National School of Tropical Medicine at Baylor College of Medicine in Houston, said: “If this tells you where there are new major clusters of fever, it tells you where to swoop in with your test kits.”

Kinsa’s latest map of fever spikes shows areas that are known to have many cases of COVID-19, the illness caused by the coronavirus. But the data also point to spots in Florida, Michigan, Arizona, and eastern Texas, where not as many cases have been reported.

Just last Saturday, Kinsa’s data indicated an unusual rise in fevers in South Florida, even though it was not known to be a COVID-19 epicenter. Within days, testing showed that South Florida had indeed become an epicenter.

Dr. Nirav Shah, a former New York State health commissioner who is an adviser to Kinsa, said real-time fever data “could speed up public health the way Twitter sped up the news cycle.”

Demand for Kinsa’s smart thermometers has skyrocketed since the coronavirus pandemic began, Mr. Singh said, and the company is now selling 10,000 a day, which is creating production problems but also multiplying the amount of data coming in each day.

The thermometers connect to a cellphone app that instantly transmits their readings to the company. Users can also enter other symptoms they feel. The app then gives them general advice on when to seek medical attention.
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Because influenza usually produces higher, more protracted fevers than common colds do, the company’s software estimates which ZIP codes appear to be hit by flu rather than by other, milder cold viruses.
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    Author

    Rick Richardson, CPA, CITP, CGMA

    Rick is the editor of the weekly newsletter, Technology This Week. You can subscribe to it by visiting the website.

    Rick is also the Managing Partner of Richardson Media & Technologies, LLC. Prior to forming his current company, he had a 28-year career in technology with Ernst & Young, the last twelve years of which he served as National Director of Technology.

    Mr. Richardson has been named to the "Technology 100"- the annual honors list of the 100 key achievers in technology in America. He has also been honored by the American Institute of CPAs with two Lifetime Achievement awards and a Special Career Recognition Award for his contributions to the profession in the field of technology.

    In 2012, Rick was inducted into the Accounting Hall of Fame by CPA Practice Advisor Magazine. He has also been named to the 100 most influential individuals in the accounting profession in America by Accounting Today magazine.

    In 2017, Rick was inducted as a Marquis Who’s Who Lifetime Achiever, a registry of professionals who have excelled in their fields for many years and achieved greatness in their industry.

    He is a sought after speaker around the world, providing his annual forecast of future technology trends to thousands of business executives, professionals, community leaders, educators and students.

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